An analysis in MSCT manifestations and clinico-pathological findings of retroperitoneal stromal tumors

Objective:To analyze the clinical and pathological characteristics and MSCT manifestations of retroperitoneal stromal tumors in order to improve the understanding and diagnostic level.Methods:The clinical materials and CT appearances of 12 cases with retroperitoneal stromal tumors confirmed by operation and pathology were retrospectively reviewed.Results:Among the 12 patients,The major clinical symptoms of the retroperitoneal stromal tumors were abdominal masses and bellyache.CT showed retroperitoneal soft tissue masses in 12 cases,the diameters of tumors were 3.0~21.0cm,mean 11.0cm.The tumors were round or oval in 7 cases,irregular in 5 cases.The tumors in 2 cases showed uniform density on plain CT scans,of which one case showed uniform enhancement and the other case non-uniform linear enhancement on contrast-enhanced CT scans.Ten cases showed unhomogeneous density on plain CT scans,all with necrotic cystic areas,hemorrhage in 2 and calcification in 2;moderate or remarkable enhancement was found in the parenchyma of the tumor,while no enhancement was found in the necrosis and cystic areas of the tumors on contrast-enhanced CT scans.There were benign tumour in 1,potential malignant tumours in 3 and malignant tumours in 8,with metastases in 3 cases.In 12 cases,all were CD117 positive,7 were CD34 positive in immunohistochemical test.Conclusion:The retroperitoneal stromal tumors usually involve middle-aged and old patients and clinical symptoms are rare,certain characteristic manifestations of the retroperitoneal stromal tumors can be shown on CT,which reflect histopathological features of the lesions,being very helpful in the diagnosis and differential diagnosis of this disease.