Preliminary clinical evaluation of CT perfusion imaging of stomach neoplasm

[Objective] The purpose of this study is preliminarily to discuss perfusion imaging technique with Multi-slice CT and its clinical application value of diagnosis in stomach neoplasm.[Methods] Thirteen patients with known stomach neoplasm performed perfusion imaging with 4 or 16-slice CT.Performing perfusion imaging in central slice of neoplasm,using CT cine scan,slice thick 10 mm/2i;with high pressure syringe,injecting quickly from right elbow-front vein,dosage 45～50 mL,injection rate(3.5～4.0) mL/s,scanning delay time 5 s,scanning total time 45 s.We performed perfusion CT post-processing using pancreatic mode of Perfusion CT software.Blood flow(BF),blood volume(BV),mean transit time(MTT),and permeability surface(PS) of gastric wall were computed for every case.[Results] BF,BV,MTT and PS of normal gastric wall were(357.24±212.44) mL/(min·100 g),(16.53±9.78) mL/100 g,(4.29±3.12) s,(36.40±39.54) mL/(min·100 g);for gastric tumors were(62.18±38.1) mL/(min·100 g),(5.21±4.58) mL/100 g,(11.79±8.18) s,(13.09±12.62) mL/(min·100 g) respectively.The P values for perfusion CT parameters between gastric tumors and normal gastric wall were 0.0017,0.014,0.04 and 0.036,respectively.[Conclusion] Perfusion CT can provide hemodynamics of gastric tumors and play a key role in the diagnosis of gastric tumors.It's clinical application prospect will be fully broad.