2011•Zhongguo shiyan fangjixue zazhiRequires access
Antioxidant Activity of Extracts from Polygonum lapathifolium
Wenyi Kang
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Abstract
Objective:To evaluate the total antioxidant activity of extracts from Polygonum lapathifolium in vitro.Method: 1,1-diphenyl-2-picryl-2-picrylhydrazyl(DPPH) radical scavenging,[2,2′-azino-bis-3-ethylbenzothizaoline-6-sulfonic acid] diammonium salt(ABTS) radical scavenging,and ferric reducing antioxidant power(FRAP) assay were used to analyze the antioxidant activity.Result: Compared with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid(Trolox) and positive control propyl gallate(PG),butylated hydroxyanisole(BHA) and 2,6-di-tert-butyl-4-methylphenol(BHT),the ethyl acetate extract and the methanol extract showed higher scavenging activity against DPPH radical,ABTS radical,and reducing antioxidant power of TPTZ than that of BHT,lower than that of PG and BHA.Conclusion: P.lapathifolium exhibited the good total antioxidant activity.In three extracts of P.lapathifolium,the ethyl acetate extract showed higher total antioxidant activity than that of the methanol extract,and the petroleum ether extract hardly had antioxidant activity.