The Relationship Between the Blood Pressure Load and Its Variability and Left Ventricular Hypertrophy in Essential Hypertensive Patients

Objective To evaluate the relationship between the BP load and its variability and left ventricular hypertrophy(LVH) in essential hypertensive patients.Methods One huandred and fourteen EH patients admitted into this hospital were taken the ABPM and echocardiography,then (according) to the LVMI,these patients were divided into two groups with or without LVH,in which we analyzed the relationship between the level of blood pressure,blood pressure load and its variability and LVH.Results (1) The levels of 24 h,daytime and nighttime SBP,SBP load and its variability in the group with LVH,were marked higher than that in the group without LVH(P0.01).(2)There were positive correlations between the level of 24h,daytime and nighttime SBP,SBP load and its variability and LVMI,but the relationship between the nighttime SBP variability and LVMI was the closest(P0.01).(3) The sensitivity,specificity and positive predicting value of the 24 h BP load more than 25% used to predict the incidence of LVH were 58.7%,89.7%,91.7% respectively.Conclusion (1) The higher levels of 24 h SBP load and its variability especially in nighttime were risk factors of LVH.(2)24 h BP load which is more than 25% may be better factor to predict the incidence of TOD in the Chinese population.