Relationship between circadian rhythms,variability of ambulatory blood pressure and left ventricular hypertrophy in patients with essential hypertension

Objective To explore the relationship between circadian rhythms,variability and parameters of ambulatory blood pressure and left ventricular hypertrophy (LVH) in patients with essential hypertension.Methods Sixty two essential hypertensive patients were selected.In the course of the practice,the parameters including the values of 24 h blood pressure and circadian blood pressure,variability of the blood pressure and left ventricular mass index (LVMI) were checked.Results The parameters of ambulatory blood pressure and LVMI in the circadian rhythm absent group were significantly higher than those in the circadian rhythm present group (P0 001).Conclusion This investigation suggests LVH in essential hypertensive patients is associated with variability enhancement of 24 h mean systolic/diastolic pressure,blood pressure variability and circadian rhythm disappearance.