The clinical analysis of 156cases on the effects of mifepristone and gestrinone treatment for postoperative patients with severe pelvic endometriosis

Objective:To investigate the effects and safety of mifepristone and gestrinone for treating for postoperative patients with severe pelvic endometriosis.Methods:156 severe pelvic endometriosis cases were analyzed retrospectively . Of the cases , 59 cases were administered mifepristone , 45 cases were administered gestrinone and other 52 cases had not taken any hormone . Recurrence rate , side effect rate were compared among these groups.Results:The recurrence rate of mifepristone group and gestrinone group was 13.6% and 11.1% , respectively , which was significantly lower than that of control group(P0.05,P0.05).The side effect rate of mifepristone group was 11.9% , which was significantly lower than that of gestrinone group(44.4%)(P0.05).Conclusion:The treatment of mifepristone and gestrinone treatment on postoperative patients with pelvic endometriosis can significantly decreased the recurrence rate of pelvic endometriosis , and elevate pregnancy rate . Mifepristone has less side effects than that of gestrinone .