A comparison of epidural ropivacaine infusion combined with fentanyl or tramadol for postoperative analgesia after abdominal hysterectomy

Objective Comparison with the effect of equivalent dose of fentanyl and tramadol in combination with ropivacaine on continuous epidural postoperative analgesia after abdominal hysterectomy is significance for safety and reasonable administration in epidural postoperative analgesia.Methods 60 patients(ASA classⅠ-Ⅱ),undergoing abdominal hysterectomy were randomly divided into three groups(20 cases in each group)to receive 0.15%ropivacaine alone(Group R),0.15%ropivacaine plus 0.000 4%fentanyl(Group F),and 0.15%ropivacaine plus 0.5%tramadol(Group T).Postoperatively all the three groups were given a initial epidural loading dose of 0.5%ropivacaine 6 ml,then the disposable micro-infusion pump was applied to continuous epidural postoperative analgesia.VAS,HR,MAP were recorded at different time.The incidence of side-effect,motor block,the time for passage of gas by anus and global satisfaction score were assessed.Results The VAS in Group F and Group T were significantly less than that in Group R(P0.05)and no significant difference were noted between Group F and Group T(P0.05).The incidence of nausea and vomiting in Group T were significantly lower than that in Group F(P0.05).HR,MAP had no significantly difference at different time points in the three groups.Compared with Group R significantly higher the global satisfaction score in Group F or Group T(P0.05).Conclusion Ropivacaine infusion in combination with fentanyl or tramadol is efficient for epidural postoperative analgesia.Ropivacaine infusion in combination with tramadol is the better choice because of the less side-effects.