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Clinical research of epidural ropivacaine infusion combined with fentanyl or tramadol for postoperative analgesia

Chunyan Zhang

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Abstract

Objective To observe the effect of fentanyl and tramadol in combination with ropivacaine on continuous epidural postoperative analgesia.Methods Sixty patients,undergoing uterine-incision delivery,were randomly divided into three groups(20 in each group) to receive 0.2% ropivacaine alone(Group R),0.2% ropivacaine plus 0.0004% fentanyl(Group F),and 0.2% ropivacaine plus 0.5% tramadol(Group T).The disposable micro-infusion pump was applied to continuous epidural postoperative analgesia.VAS were recorded at different time.The incidence of side-effect was assessed.Results The VAS in Group F or Group T were significantly less than that in Group R(P0.05)and no significant difference were noted between Group F and Group T(P0.05).The incidence of nausea and vomiting in Group T was significantly lower than that in Group F(P0.05).Conclusions Ropivacaine infusion combined with tramadol is the better choice because of the less side-effects.

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Objective To observe the effect of fentanyl and tramadol in combination with ropivacaine on continuous epidural postoperative analgesia.Methods Sixty patients,undergoing uterine-incision delivery,were randomly divided into three groups(20 in each group) to receive 0.2% ropivacaine alone(Group R),0.2% ropivacaine plus 0.0004% fentanyl(Group F),and 0.2% ropivacaine plus 0.5% tramadol(Group T).The disposable micro-infusion pump was applied to continuous epidural postoperative analgesia.VAS were recorded at different time.The incidence of side-effect was assessed.Results The VAS in Group F or Group T were significantly less than that in Group R(P0.05)and no significant difference were noted between Group F and Group T(P0.05).The incidence of nausea and vomiting in Group T was significantly lower than that in Group F(P0.05).Conclusions Ropivacaine infusion combined with tramadol is the better choice because of the less side-effects.

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Available abstract

Objective To observe the effect of fentanyl and tramadol in combination with ropivacaine on continuous epidural postoperative analgesia.Methods Sixty patients,undergoing uterine-incision delivery,were randomly divided into three groups(20 in each group) to receive 0.2% ropivacaine alone(Group R),0.2% ropivacaine plus 0.0004% fentanyl(Group F),and 0.2% ropivacaine plus 0.5% tramadol(Group T).The disposable micro-infusion pump was applied to continuous epidural postoperative analgesia.VAS were recorded at different time.The incidence of side-effect was assessed.Results The VAS in Group F or Group T were significantly less than that in Group R(P0.05)and no significant difference were noted between Group F and Group T(P0.05).The incidence of nausea and vomiting in Group T was significantly lower than that in Group F(P0.05).Conclusions Ropivacaine infusion combined with tramadol is the better choice because of the less side-effects.

Key concepts: Ropivacaine, Tramadol, Medicine, Fentanyl, Anesthesia, Nausea, Vomiting, Surgery

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