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Clinical Application Value of MR Fat-suppression Sequence in Breast Neoplasm

Yuan Li

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Abstract

Objective To study the clinical value of fat-suppression(FS)sequence and dynamic contrast-enhanced MRI in judging the nature of breast neoplasm.Methods Sixty patients with breast neoplasm(including malignant lesions in 40 cases and benign lesions in 20 cases)proved by histopathology were reviewed.All patients were undergone FS sequence and 30 cases underwent dynamic contrast-enhanced MRI examinations,time-signal curves were acquired.Results 22 malignant lesions in 20 cases and 46 benign lesions in 40 cases were found by FS.Dynamic contrast-enhanced MRI showed 18 malignant and 20 benign lesions.The malignant lesions had visible contrast-enhancement of administration of Gd-DTPA.Type Ⅲ curve was showed in 16 lesions(malignant in 14 and benign in 2),type Ⅱ in 5(malignant in 3 and benign in 2)and type Ⅰ in 17(malignant in 1 and benign in 16).There was significant difference between benign and malignant tumors on the type of time-signal curve(P0.01).Type Ⅲ curve was more seen in malignant neoplasms,Type Ⅱ prompted suspicious malignant tumors,while TypeⅠwas more seen in benign.Conclusion FS sequence and dynamic contrast-enhanced MRI is useful to make a specificity and accurate diagnosis for breast neoplasm.

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Objective To study the clinical value of fat-suppression(FS)sequence and dynamic contrast-enhanced MRI in judging the nature of breast neoplasm.Methods Sixty patients with breast neoplasm(including malignant lesions in 40 cases and benign lesions in 20 cases)proved by histopathology were reviewed.All patients were undergone FS sequence and 30 cases underwent dynamic contrast-enhanced MRI examinations,time-signal curves were acquired.Results 22 malignant lesions in 20 cases and 46 benign lesions in 40 cases were found by FS.Dynamic contrast-enhanced MRI showed 18 malignant and 20 benign lesions.The malignant lesions had visible contrast-enhancement of administration of Gd-DTPA.Type Ⅲ curve was showed in 16 lesions(malignant in 14 and benign in 2),type Ⅱ in 5(malignant in 3 and benign in 2)and type Ⅰ in 17(malignant in 1 and benign in 16).There was significant difference between benign and malignant tumors on the type of time-signal curve(P0.01).Type Ⅲ curve was more seen in malignant neoplasms,Type Ⅱ prompted suspicious malignant tumors,while TypeⅠwas more seen in benign.Conclusion FS sequence and dynamic contrast-enhanced MRI is useful to make a specificity and accurate diagnosis for breast neoplasm.

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Available abstract

Objective To study the clinical value of fat-suppression(FS)sequence and dynamic contrast-enhanced MRI in judging the nature of breast neoplasm.Methods Sixty patients with breast neoplasm(including malignant lesions in 40 cases and benign lesions in 20 cases)proved by histopathology were reviewed.All patients were undergone FS sequence and 30 cases underwent dynamic contrast-enhanced MRI examinations,time-signal curves were acquired.Results 22 malignant lesions in 20 cases and 46 benign lesions in 40 cases were found by FS.Dynamic contrast-enhanced MRI showed 18 malignant and 20 benign lesions.The malignant lesions had visible contrast-enhancement of administration of Gd-DTPA.Type Ⅲ curve was showed in 16 lesions(malignant in 14 and benign in 2),type Ⅱ in 5(malignant in 3 and benign in 2)and type Ⅰ in 17(malignant in 1 and benign in 16).There was significant difference between benign and malignant tumors on the type of time-signal curve(P0.01).Type Ⅲ curve was more seen in malignant neoplasms,Type Ⅱ prompted suspicious malignant tumors,while TypeⅠwas more seen in benign.Conclusion FS sequence and dynamic contrast-enhanced MRI is useful to make a specificity and accurate diagnosis for breast neoplasm.

Key concepts: Medicine, Histopathology, Neoplasm, Radiology, Dynamic contrast-enhanced MRI, Contrast enhancement, Magnetic resonance imaging, Dynamic contrast

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