Clinical evaluation of intraarterial thrombolysis in acute cerebral infarction

Objective To present a retrospective analysis of the clinical outcome in patients treated by local intra-arterial thrombolysis (LITT). Using urokinase for acute ischemic stroke of the anterior or posterior arterial circulation.Methods Twenty-six patients were treated with LITT using urokinase. The effects all patients were assessed by using angiography, brain CT and stroke scale before and after treatment. Results Among 26 patients, the complete reperfusion of blood vessel appeared in 7 and partial reperfusion in 11.The efficiency rate reached 78%.Conclusions Cerebral arterial thrombolysis with UK can improve neurologic function defect in 84% of patients with acute ischemic stroke after 15 days, suggesting one of the best ways for treatment.