Clinical curative effect analysis of rosiglitazone combined with metformin in treatment of type 2 diabetes

Objective To observe the clinical curative effect of rosiglitazone combined with metformin in treatment of type 2 diabetes.Methods Eighty cases of type 2 diabetes patients were randomly divided into observation group(rosiglitazone combined with metformin) and control group(metformin),each group had 40 cases.Fasting blood-glucose(FBG),2-hour postprandial blood-glucose(2hPG) and glycosylated hemoglobin(HbA1c) changes were observed and compared before and after treatment between two groups.Results The total effective rate of the observation group was 95.0%,the total effective rate of control group was only 75.0%,the difference had statistical significance(P 0.05).Before treatment,the level of the FBG,2hPG,HbA1c between two groups had no significant difference(P 0.05),after 3 months treatment,FBG,2hPG,HbA1c between two groups were compared with pre-treatment significantly reduced,and the observation group reduced more significantly than the control group(P 0.05).Conclusion The efficacy of Rosiglitazone and Metformin in the treatment of type 2 diabetes is exactly,it can effectively control blood sugar,and it has fewer adverse reactions,it is worthy of exten sive promotion and application.