Distribution Characteristics of TCM Syndrome Differentiation in Patients with Primary Lung Cancer

Objective To investigate the characteristics of traditional Chinese medicine(TCM)syndrome differentiation in 152 hospitalized patients with primary lung cancer in Peking Union Medical College Hospital(PUMCH).Methods One hundred fifty-two patients were investigated by questionnaire survey and computer identifying syndromes.Criterions of symdrome differentiation of lung cancer were put out based on The Guidelines of Clinical Research on New Chinese Medicine and The People's Republic of China's National Standard-Clinic Terminology of TCM Diagnosis and Treatment-Syndromes and combined with the clinical experience of distinguished TCM Professor Guo Saishan.Results(1)Distributions of the 9 basic syndromes(blood stasis syndrome,deficiency of yin syndrome,stagnation of qi syndrome,damp-heat syndrome,deficiency of qi syndrome,phlegm-heat syndrome,phlegm-dampness syndrome,deficiency of yang syndrome,fire syndrome)was different(P0.01).In 5 zang-organs,lung was involved in the first place(32.1%),liver and heart followed(22.6%,22.0%,respectively).(2)Frequency of differentiation types:31.6%(48/152)patients were divided into 2-syndrome differentiation group,33.6%(51/152)patients into 2-syndrome group;32.9%(50/152)patients into 3-syndrome group or above;3 patients could not be divided into any group.(3)Clinical staging was positively correlated with TCM syndromes(P0.05).The frequency of patients with blood stasis syndromes in each staging was as follows:staging Ⅰ 61.5%(16/26),staging Ⅱ 60.0%(6/10),staging ⅢI 74.5%(38/51),staging Ⅳ 80.0%(52/65).(4)There was significant difference in distribution of TCM syndromes between smoking and non-smoking patients with lung cancer(P0.05).Conclusion Blood stasis syndrome is the most common in basic syndromes.In 5 zang-organs,lung was involved in the first place.Clinical staging was positively correlated with TCM syndromes.Blood stasis syndrome was the most frequent syndrome in each stage of lung cancer.Blood stasis syndrome played an important role in the pathogenesis of lung cancer.And it could be a guide in syndrome-differentiation.Phlegm-heat syndrome and damp-heat syndrome are common in smoking patients with lung cancer.