Serum Glucose Concentrations Independently Predict Early Mortality in Patients with Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention

Objective To assess the predictive value of admission glucose concentrations in hospital outcome in patients with acute STEMI undergoing primary percutaneous coronary intervention(PCI).Methods One hundred and seventy nine consecutive patients with acute STEMI who were treated with primary PCI within 24 hours after onset of symptoms were classified according to serum glucose levels at admission: 7.0 mmol/L(group A,n = 68),7.0 to 11.0 mmol/L(group B,n = 74),and 11.0 mmol/L(group C,n = 37).All patients received relative chemical tests.Mortality and total cardiac affairs in hospital were recorded.Results Among the three groups,there were no significance in age,gender,history of smoking,hypertension,hyperlipdemia,old myocardial infarction,prodromal angina pectoris,period from onset of chest pain to PCI.(P0.05),but compared about history of diabetes mellitus,there was a significance(P=0.000).Compared with group A and B,admission glucose and admission white blood cell counts were higher in group C,there was significance(P0.05).Peak value of CK-MB was higher in group B than that in group A(P0.05).Numbers of disease vessels were the most in group C(P0.05).In hospital mortality and total cardiac affairs were significantly higher in group C compared with group B and group A(20.7%,4.1%,and 2.9% respectively in mortality,P=0.001;37.8% vs 27% vs 16.2% in MACE,P=0.045).Conclusion In STEMI patients undergoing emergency PCI,admission glucose levels are predictive for in hospital morality and total cardiac affairs.Knowledge of admission glucose levels may improve initial bedside risk stratification.