Predictive value of admission serum glucose level on hospitalized mortality in acute myocardial infarction after percutaneous coronary intervention.

Objective To study the predictive value immediate serum glucose(SG) level on admission hospitalized mortality in acute myocardial infarction(AMI) after emergency percutaneous coronary intervention(PCI). Methods A total of 456 non-diabetics AMI patients after PCI, male 319, female 137, aged 29 - 85 years, mean aged 61.30 years, were divided into 3 groups according to SG levels on admission:Group A, SG 7.8 mmol/L, n = 248; Group B, 7.8 mmol/L ≤ SG ≤ 11.1 mmol/L, n = 156; Group C, SG 11.1 mmol/ L, n = 52. The incidence of cardiac failure, arrhythmia, cardiac death, reinfarction, post-infarctional angina pectoris and major adverse cardiac events(MACE) among 3 groups were compared. Results There were no significant differences(P 0.05) among 3 groups in age, sex, family history of coronary artery disease, history of smoking, hypertension, atrial fibrillation, lesion of anterior descending branch and right coronary arteries, multiple coronary artery disease, post-infarctional angina pectoris and chest pain period from onset to PCI; Compared with group A and B, there were significant differences in Killip’s ≥ 2,more than one position MI and white blood cell counts in group C(P 0.05); Re-MI was higher in group C than that in group A(P 0.05). Malignant arrhythmia were higher in group B and C than that in group A(P 0.05); In hospitalized mortality and incidence of MACE were significantly higher in group C, compared with group A and B (13.7 % vs 4.5 % vs 1.6 % in mortality, 46.2 % vs 34.0 % vs 19.0 % in MACE,P 0.001).Conclusion It is demonstrated that there is higher hospitalized mortality and occurrence rate of total cardio-vascular events in AMI patients with elevated immediate admission SG level after treating by emergency PCI. Thus the immediate admission hyperglycemia in AMI patients may predict poor prognosis.