Analysis of the Correlation of High-risk HPV(16/18 type)of Cervical Tissue Infection with Cervical Cancer and Precancerous Lesions

Objective To compare and analyze the correlation of high-risk HPV(16/18 type) of cervical tissue infection with cervical cancer and precancerous lesions by observing the HPV(human papilloma virus)infection of women with cervical lesions.Methods 656 patients suspected with cervical lesions treated in gynecology of our hospital were selected as the study objects.Biopsy and professional pathological diagnosis were adopted;HPV-16 and HOV-18 were detected in genetics,then the results were analyzed.Results Compared to group without cervical cancer,the positive rates of high risk HPV DNA of CIN Ⅰ group,CINⅡ/Ⅲ group and cervical cancer group were increased significantly(P0.05);and the positive rates of high risk HPV DNA of CINⅡ/Ⅲ group and cervical cancer group were increased significantly compared to CIN Ⅰ group(P0.05);the risk degree was higher after infecting with HPV-16 and HPV-18,OR were 48.85 and 26.00 respectively;the risk degree of CINⅡ/Ⅲ was higher too,OR were 11.59 and 19.36 respectively.Conclusion High-risk HPV(16/18 type) of cervical tissue infection has certain correlation with cervical cancer and precancerous lesions.Attention should be paid to HPV infection and self-protection,so as to avoid HPV infection.