2014•Clinical Medicine & EngineeringRequires access

Clinical Value of PCT Combined with CRP in the Diagnosis of Neonatal Septicemia

Yang Qiaoyu

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Abstract

Objective To explore diagnostic value of procalcitonin(PCT) and C reactive protein(CRP) for neonatal septicemia.Methods From January 2011 to January 2014, 80 cases of neonatal septicemia and 80 cases of healthy neonate in our hospital were selected as the observation group and the control group respectively. The PCT and CRP levels were detected by immunochromatographic method and immuno-scatter turbidmetry respectively, and and compared between two groups. The positive predictive value, specificity and sensitivity of PCT and CRP were compared. Results The CRP level and PCT level of observation group were significantly higher than those of control group(P 0.05). There were no statistical differences in the sensitivity, positive predictive value between CRP and PCT(P 0.05), but there was statistical difference in the specificity between CRP and PCT(P 0.05). Conclusions Both PCT and CRP are the sensitive detection indices for neonatal septicemia, and have important significance for the diagnosis of neonatal septicemia.

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What this paper is about

Objective To explore diagnostic value of procalcitonin(PCT) and C reactive protein(CRP) for neonatal septicemia.Methods From January 2011 to January 2014, 80 cases of neonatal septicemia and 80 cases of healthy neonate in our hospital were selected as the observation group and the control group respectively. The PCT and CRP levels were detected by immunochromatographic method and immuno-scatter turbidmetry respectively, and and compared between two groups. The positive predictive value, specificity and sensitivity of PCT and CRP were compared. Results The CRP level and PCT level of observation group were significantly higher than those of control group(P 0.05). There were no statistical differences in the sensitivity, positive predictive value between CRP and PCT(P 0.05), but there was statistical difference in the specificity between CRP and PCT(P 0.05). Conclusions Both PCT and CRP are the sensitive detection indices for neonatal septicemia, and have important significance for the diagnosis of neonatal septicemia.

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Available abstract

Objective To explore diagnostic value of procalcitonin(PCT) and C reactive protein(CRP) for neonatal septicemia.Methods From January 2011 to January 2014, 80 cases of neonatal septicemia and 80 cases of healthy neonate in our hospital were selected as the observation group and the control group respectively. The PCT and CRP levels were detected by immunochromatographic method and immuno-scatter turbidmetry respectively, and and compared between two groups. The positive predictive value, specificity and sensitivity of PCT and CRP were compared. Results The CRP level and PCT level of observation group were significantly higher than those of control group(P 0.05). There were no statistical differences in the sensitivity, positive predictive value between CRP and PCT(P 0.05), but there was statistical difference in the specificity between CRP and PCT(P 0.05). Conclusions Both PCT and CRP are the sensitive detection indices for neonatal septicemia, and have important significance for the diagnosis of neonatal septicemia.

Key concepts: Procalcitonin, Medicine, C-reactive protein, Neonatal sepsis, Predictive value, Internal medicine, Gastroenterology, Statistical significance

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