Analysis on Detection for Chlamydia Trachomatis and Mycoplasma and Drug Resistance of Mycoplasma in 1636 Cases of Cervical Samples

Objective To investigate the infection rates of Ureaplasma urealyticum(UU),Mycoplasma hominis(MH) and Chlamydia trachomatis(CT) in cervix uteri. Methods The CT, UU and MH were detected in 1636 cases of cervical samples by using the culture for pathogens and golden-standard method. Results (1) The total infection rate of three pathogens was 49.08%(803/1 636), among which the rate of one pathogen infection was 39.06%(639/1 636),and the mixed infection rate was 10.02%(164/1 636); the infection rates of Mycoplasma and Chlamydia trachomatis were 37.47%((613)/(1 636)), and 11.61%(190/1 636) respectively.(2)The high risk age of Mycoplasma and Chlamydia trachomatis infection was from 21 to 40 years, accounted for 79.58% of the positive specimens.(3)The highest drug resistance rate of My-coplasma was actinospectacin (90%). The drug resistance rates of the Mycoplasma hominis and mixed infection of both UU and MH against actinospectacin,roxithromycin,erythromycin were over 80%. The most sensitive antibiotics was josamycin, the (second) was doxycycline. Conclusion (1)The UU,CT and MH are the major pathogens in female cervix uteri.The range of infection rates from high to low is UUCTMH.(2) The drug resistance strains to Mycoplasma is serious. Therefore, we (should) choose the correct antibiotics according to the drug sensitivity test.