Cytogenetic Study of 37 Patients with Primary Amenorrhea

Objective To discuss the correlation between sex chromosomal abnormalities and gonadal dysgenesis.Methods The chromosomal G banded karyotypes of 37 cases with primary amenorrhea were analyzed.Results 15 patients with chromosomal abnormalities,including 10 cases of X chromosome aneuploidy,3 with structural abnormalities,and 2 with Y chromosome,were found.The ratio of abnormality was 40.5%.Conclusions Sex chromosome abnormality is one of the main factors of primary amenorrhea.The chromosome examination is necessary for the determination the pathogeny and therapy of amenorrhea.