2008Journal of Clinical Transfusion and Laboratory MedicineRequires access

Distribution of Bacteria in Urinary Tract Infection and Analysis of Drug Resistance of Escherichia coli

PU Yue-che

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Abstract

Objective To investigate the distribution of pathogens and resistance of Escherichia coli with urinary tract infection for the guidance of rational use of antibiotics.Methods To analyse the distribution of bacteria isolated from urine in our hospital and study the antimicrobial resistance of strains of E.coli.Results The most common pathogens in urinary tract infection were E.coli(40.31%),next were Fungi and Enterococcus.For the antibiotic ampicillin,cefalotin,nalidixic acid and ticarcillin,the rates of resistance of E.coli were more than 90%.For the antibiotic cefoxitin and nitrofurantoin,the rates of resistance of E.coli were less than 10%.All of E.coli strains were sensitive to impenem.Conclusion E.coli is still the primary urinary pathogen in our hospital,the clinics should choose the appropriate antibiotic agents according to the culture and in vitro susceptibility of bacteria.

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Objective To investigate the distribution of pathogens and resistance of Escherichia coli with urinary tract infection for the guidance of rational use of antibiotics.Methods To analyse the distribution of bacteria isolated from urine in our hospital and study the antimicrobial resistance of strains of E.coli.Results The most common pathogens in urinary tract infection were E.coli(40.31%),next were Fungi and Enterococcus.For the antibiotic ampicillin,cefalotin,nalidixic acid and ticarcillin,the rates of resistance of E.coli were more than 90%.For the antibiotic cefoxitin and nitrofurantoin,the rates of resistance of E.coli were less than 10%.All of E.coli strains were sensitive to impenem.Conclusion E.coli is still the primary urinary pathogen in our hospital,the clinics should choose the appropriate antibiotic agents according to the culture and in vitro susceptibility of bacteria.

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Available abstract

Objective To investigate the distribution of pathogens and resistance of Escherichia coli with urinary tract infection for the guidance of rational use of antibiotics.Methods To analyse the distribution of bacteria isolated from urine in our hospital and study the antimicrobial resistance of strains of E.coli.Results The most common pathogens in urinary tract infection were E.coli(40.31%),next were Fungi and Enterococcus.For the antibiotic ampicillin,cefalotin,nalidixic acid and ticarcillin,the rates of resistance of E.coli were more than 90%.For the antibiotic cefoxitin and nitrofurantoin,the rates of resistance of E.coli were less than 10%.All of E.coli strains were sensitive to impenem.Conclusion E.coli is still the primary urinary pathogen in our hospital,the clinics should choose the appropriate antibiotic agents according to the culture and in vitro susceptibility of bacteria.

Key concepts: Microbiology, Nalidixic acid, Escherichia coli, Nitrofurantoin, Ampicillin, Cefoxitin, Ticarcillin, Antibiotic resistance

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