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Research and Application of Virus Vectors in Gene Therapy

WU Jun-yong

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Abstract

Gene therapy relies on the delivery of normal gene or medicative gene into human cells,it may correct the gene defects or play role in treatment of diseases.It is a promising treatment for several acquired and inherited diseases,but their success is depends on vector.At present,the main vectors are virus vectors and non-virus vectors,but viral vectors are the most widely vectors used in gene therapy.This article focused on recent application and improvement of virus vectors in gene therapy.

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What this paper is about

Gene therapy relies on the delivery of normal gene or medicative gene into human cells,it may correct the gene defects or play role in treatment of diseases.It is a promising treatment for several acquired and inherited diseases,but their success is depends on vector.At present,the main vectors are virus vectors and non-virus vectors,but viral vectors are the most widely vectors used in gene therapy.This article focused on recent application and improvement of virus vectors in gene therapy.

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Available abstract

Gene therapy relies on the delivery of normal gene or medicative gene into human cells,it may correct the gene defects or play role in treatment of diseases.It is a promising treatment for several acquired and inherited diseases,but their success is depends on vector.At present,the main vectors are virus vectors and non-virus vectors,but viral vectors are the most widely vectors used in gene therapy.This article focused on recent application and improvement of virus vectors in gene therapy.

Key concepts: Genetic enhancement, Vector (molecular biology), Vectors in gene therapy, Virus, Gene delivery, Gene, Viral vector, Adeno-associated virus

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