2004•Unpublished venueRequires access

Diagnostic and Prognostic Value of NT-proBNP in Heart Failure of Coronary Heart Disease

Lijuan Zhou

Abstract

Objective:To investigate the diagnostic and prognostic values of NT-pro BNP in symptomatic heart failure.Methods:Fifty-eight and13coronary heart disease patients were enrolled into heart failure group and non heart failure group respectively.Left ventricular function was measured with echocardiography.Plasma NT-pro BNP was determined with enzyme immunoassay method.All patients were followed up.Results:Compared with non heart failure group and normal group,heart failure group had a higher plasma NT-pro BNP.The plasma NT-pro BNP was significantly associated with left ventricular function parameters of eˉchocardiography.In the heart failure group,the plasma NT-pro BNP had no significant difference between the dead and survival groups.Conclusion:In coronary heart disease patients,the plasma NT-pro BNP signifˉicantly elevated in heart failure,and it was a useful marker to detect these patients.According to our follow-up results,the plasma NT-pro BNP couldn't predict short-term cardiogenic death in heart failure.

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Key concepts: Heart failure, Medicine, Internal medicine, Cardiology, Natriuretic peptide, Heart disease