A Study on Early Diagnosis Criteria of Hepatic Cirrhosis

Purpose: The change of the hepatic blood perfusion quantity (HPQ) may be one of the clinical manifestations of hepatic cirrhosis. So determination of HPQ has clinical value for studying on early diagnosis criteria and determining the degree of hepatic cirrhosis. Materials and Methods: 30 cases who had been diagnosed hepatic cirrhosis entered into study group and 8 cases whose liver function were normal entered into contral group. These patient's T max , T 1/2 , K, HPQ determined by 99m Tc RBC and SPECT dynamic scanning. Results: The results showed that the levels of HPQ in 90% (27/30) patients with hepatic cirrhosis were decreased significantly (P0.01). There were significant defference of other items between the study group and control group (P0.01). 10% (3/30)patients with hepatic cirrhosis had portal hypertension and their HPQ and K value were higher than control group. Conclusion: HPQ may be one of the early diagnosis criteria. The lower degree of HPQ and K value was parallel to the degree of cirrhosis. The drugs which decreas portal vein pressure could be accurately seleted based on the value of HPQ with portal hypertension.