Use the Conventional Papanicolaou Smear by Improved Take-samples in Screening Cervical Carcinoma in People

Objective:To investigate the value of conventional Papanicolaou smear (Pap) improved by takesamples in screening cervical carcinoma.Methods:Conventional Pap smear by improved take-samples,liquid-based cytology test,hybrid capture Ⅱ human papillomavarus test were performed in 500 women of 30-59 years old without screening cervical cancer in 3 years in Shang Mei-lin community of Shenzhen Futian region from December 2007 to March 2008.We obtained samples of Pap by a broom-type sampling device (take-samples used for LCT) with splitsampling method.The positive threhold of cervical cytology was atypical squamous cells of undetermined sign (ASCUS).The women with either testing result of Pap,LCT or HPV positive received multi-spot biopsy under colposcopy.The pathology results were the final diagnosis criteria to evaluate the value of two cervical cytology for screening cervical cancer.Results:The best screening cervical intraepithelial neoplasia (CIN)Ⅱ threhold of cervical cytology was ASCUS;There were no significant differences of screening effectiveness and unsatisfactory rate between Pap with improved take-samples and LCT;The complete concordance of diagnosis between Pap and LCT was 86.8%,The higher grade cervical lesion,the better concordance of diagnosis between Pap and LCT.Conclusions:Pap smear with improved take-samples is economic and effective and is worth popularizing in screening cervical carcinoma.