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2006•Tianjin Yike Daxue xuebaoRequires access

Relationship between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus

Shiduo Song

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Abstract

Objective: To investigate the correlation between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus.Methods: The serum IgG antibodies of mycoplasma pneumoniae or chlamydia from 40 SLE patients and 40 age-sex-matched healthy subjects were tested by quantitative ELISA.Results: The positive rate of IgG antibodies of mycoplasma pneumoniae was 47.5% in SLE patients.It is significantly higher than that in control(25.0%)(P0.05).There was no obvious difference in the positive ratio of IgG antibodies of chlamydia between two groups.Antibody activities of mycoplasma pneumoniae or chlamydia in positive were not significantly different between two groups.Conclusion: SLE is correlated to mycoplasma pneumoniae infection,which may potentiate an attack of SLE.Correlation between SLE and IgG antibodies to Chlamydia is not found.

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What this paper is about

Objective: To investigate the correlation between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus.Methods: The serum IgG antibodies of mycoplasma pneumoniae or chlamydia from 40 SLE patients and 40 age-sex-matched healthy subjects were tested by quantitative ELISA.Results: The positive rate of IgG antibodies of mycoplasma pneumoniae was 47.5% in SLE patients.It is significantly higher than that in control(25.0%)(P0.05).There was no obvious difference in the positive ratio of IgG antibodies of chlamydia between two groups.Antibody activities of mycoplasma pneumoniae or chlamydia in positive were not significantly different between two groups.Conclusion: SLE is correlated to mycoplasma pneumoniae infection,which may potentiate an attack of SLE.Correlation between SLE and IgG antibodies to Chlamydia is not found.

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Available abstract

Objective: To investigate the correlation between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus.Methods: The serum IgG antibodies of mycoplasma pneumoniae or chlamydia from 40 SLE patients and 40 age-sex-matched healthy subjects were tested by quantitative ELISA.Results: The positive rate of IgG antibodies of mycoplasma pneumoniae was 47.5% in SLE patients.It is significantly higher than that in control(25.0%)(P0.05).There was no obvious difference in the positive ratio of IgG antibodies of chlamydia between two groups.Antibody activities of mycoplasma pneumoniae or chlamydia in positive were not significantly different between two groups.Conclusion: SLE is correlated to mycoplasma pneumoniae infection,which may potentiate an attack of SLE.Correlation between SLE and IgG antibodies to Chlamydia is not found.

Key concepts: Chlamydia, Mycoplasma pneumoniae, Mycoplasma, Antibody, Immunology, Medicine, Systemic lupus erythematosus, Chlamydiaceae

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