Advances in Study on Antidepressants for Treatment of Functional Gastrointestinal Disorders

Functional gastrointestinal disorders(FGIDs) include functional dyspepsia(FD) and irritable bowel syndrome(IBS).In recent years,increasing evidences have shown that psychological factor plays an important role in the pathogenetic process of FGIDs.Antidepressants as a therapy for FGIDs have been widely used in clinical practice.In contrast to standard-dose,low-dose antidepressants have the advantage of equivalence in therapeutic efficacy,less sideeffect and high compliance.This article reviewed the advances in study on antidepressants for treatment of FGIDs.