Correlations of serum human chorionic gonadotropin,calcium,uric acid,creatinine levels and pregnancy-induced hypertension

Objective To investigate the relationships between the maternal serum human chorionic gonadotropin(β-HCG),calcium,uric acid,creatinine levels and pregnancy induced hypertension(PIH).Methods Chemiluminescence was adopted to detect β-HCG and biochemical assay was used to measure calcium,uric acid and creatinine.Results Women with PIH had significantly higher β-HCG level than those without PIH;during middle and late pregnancy,serum calcium was significantly lower while uric acid and creatinine increased in women with PIH,and the difference was significant(P 0.01-0.05).Conclusion In the second trimester,serum β-HCG can predict the occurrence of PIH.Calcium decline during middle and late pregnancy may be a harbinger of PIH while elevated uric acid and creatinine may indicate the damage of renal function.