Diagnostic value of cTnI and CK-MB combination detection in acute myocardial infarction

Objective To explore the clinical value of cardiac troponin I(cTnI) and creatine kinase MB(CK-MB) combination detection in the diagnosis of acute myocardial infarction(AMI).Methods Serum of 62 AMI patients and 50 healthy people were examined for cTnI,CK and CK-MB,performed with Rhodes and Hitachi autobiochemical analysis.The data were analyzed statistically.Results In AMI group,concentrations of cTnI,CK and CK-MB were significantly higher than those in control group(P0.01).Sensitivity of combined markers(cTnI and CK-MB) was 96.7%,higher than cTnI,CK and CK-MB respectively.In AMI dynamic detection,combined markers were more sensitive in early stage of AMI and sustained positive for a longer time.Conclusion Combined markers of cTnT and CK-MB improve the detective rate of AMI in early stage and have a wider diagnostic time window.