2003•Acta Scientiae CircumstantiaeRequires access
A study on the genetic toxicity of formaldehyde emitted from wood-based panels
Yang Xu
Open publisher page 2 citations
Abstract
In order to understand the genetic toxicity of formaldehyde emitted from wood-based panels the studies were carried out on cell DNA damages:(1) Single cell gel electrophoresis (SCGE) test in vitro on rat liver cells and human lymphocytes. (2) Micronucleus test in vivo on mice marrow cells. The results showed that, whether in vitro or in vivo test, there were significant DNA damage in these cells at the concentrations of 1.24 mg/m 3 and 3.71 mg/m 3. The higher of formaldehyde concentration may lead to the crosslinks of DNA.