2006•ZhongcaoyaoRequires access
Effect of 2-hydroxypropyl-β-cyclodextrin on solubility and stability of garlic oil
Song Hong-tao
Open publisher page 1 citations
Abstract
Objective To investigate the effects of 2-hydroxypropyl-β-cyclodextrin(HP-β-CD) on the solubility and stability of garlic oil.Methods The solubility of allicin of garlic oil in various concentration of HP-β-CD water solution was determined by GC.The content of allicin was used as an index to compare the stability of garlic oil HP-β-CD water solution with garlic oil Tween-80 water solution under the conditions of 40 ℃,60 ℃,and light(4 500 lx).The effects of pH value,antioxidants,nitrogen gas,and sterilizing on the stability of allicin of garlic oil in 5% HP-β-CD water solution were investigated.Results The solubility of allicin of garlic oil in water could be improved remarkably by HP-β-CD and increased linearly along with the increasing of HP-β-CD concentration.The allicin of garlic oil was more stable in HP-β-CD water solution than in Tween-80 water solution while in pH value 5.0 and with nitrogen gas.The stablity of allicin of garlic oil was decreased under the conditions of heating,lighting,or adding antioxidants.Conclusion HP-β-CD could evidently increase the solubility of allicin of garlic oil in water and improve its stability.