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2004•Journal of Clinical StomatologyRequires access

The study of Platelet-rich plasma on differentiation of bone marrow stromal cells into osteoblasts in vitro

Yongshu Li

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Abstract

Objective:To explore the effects of Platelet-rich plasma(PRP) on the induced osteoblast of bone marrow stromal cells(BMSCs).Method: PRP were extracted from autologous venous blood and then dissolved into DMEM medium. BMSCs were cultured with the prepared special medium, and then stained for alkaline phosphatase (ALP) , measured for the amount of osteocalcin in the culture medium. Result:After BMSCs were cultured with the prepared medium,the expressions of ALP and the amount of osteocalcin were increased greatly.Conclusion:The results show PRP can promote BMSCs differentiated into osteoblasts in vitro.

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What this paper is about

Objective:To explore the effects of Platelet-rich plasma(PRP) on the induced osteoblast of bone marrow stromal cells(BMSCs).Method: PRP were extracted from autologous venous blood and then dissolved into DMEM medium. BMSCs were cultured with the prepared special medium, and then stained for alkaline phosphatase (ALP) , measured for the amount of osteocalcin in the culture medium. Result:After BMSCs were cultured with the prepared medium,the expressions of ALP and the amount of osteocalcin were increased greatly.Conclusion:The results show PRP can promote BMSCs differentiated into osteoblasts in vitro.

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Available abstract

Objective:To explore the effects of Platelet-rich plasma(PRP) on the induced osteoblast of bone marrow stromal cells(BMSCs).Method: PRP were extracted from autologous venous blood and then dissolved into DMEM medium. BMSCs were cultured with the prepared special medium, and then stained for alkaline phosphatase (ALP) , measured for the amount of osteocalcin in the culture medium. Result:After BMSCs were cultured with the prepared medium,the expressions of ALP and the amount of osteocalcin were increased greatly.Conclusion:The results show PRP can promote BMSCs differentiated into osteoblasts in vitro.

Key concepts: Osteocalcin, Platelet-rich plasma, Stromal cell, Alkaline phosphatase, In vitro, Bone marrow, Chemistry, Osteoblast

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