Analysis of the diagnostic methods and etiological factors in patients with fever of unknown origin

Objective To analyze the diagnostic methods and etiological factors in patients with fever of unknown origin (FUO).Methods The clinical data of 362 patients with FUO,who were treated in hospital since March 2001 to May 2005,were retrospectively analyzed.Results Among the 362 patients,316 patients were definitely diagnosed (87.3%).Among the 316 definite diagnosis patients,176 cases were infectious disease,134cases were becterial infection (134 cases were virus infection,5 cases were fungus infection and 3 case belonged to other disese),140 cases were non-infections disease (65 cases were collagen vascular diseases,61 cases were malignant tumor and 14 cases belonged to other diseases).46 cases remained origin-unknown until they were discharged from hospital.Conclusion In the diagnosis of FUO,we should manage to collect pathogenic,immunologic and pathologic evidences.Infectious di-seases,collagen vascular diseases and malignant tumors are the main causes of FUO.