Wei Cui
Abstract
Sildenafil is a selective phosphodiesterase type 5 (PDE5) inhibitor.Sildenafil produces pulmonary vasodilatation by selectively inhibiting PDE5 and increasing intracellular concentrations of cyclic guanosine monophosphate (cGMP).Sildenafil can depress pulmonary arterial hypertention.
A significance statement is not available in the OpenAlex record.
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Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
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Sildenafil is a selective phosphodiesterase type 5 (PDE5) inhibitor.Sildenafil produces pulmonary vasodilatation by selectively inhibiting PDE5 and increasing intracellular concentrations of cyclic guanosine monophosphate (cGMP).Sildenafil can depress pulmonary arterial hypertention.
Key concepts: Medicine, Sildenafil, Cardiology, Internal medicine, Pharmacology, Anesthesia