Clinical values of prealbumin and C reactive protein in early diagnosis of neonatal infectious diseases

Objective:To explore the clinical application values of prealbumin(PA) and C reactive protein(CRP) in early diagnosis of neonatal infectious diseases.Methods:Forty-eight neonates without infectious diseases were selected as control group,the levels of PA and CRP in 348 neonates with infectious diseases were researched.Results:The results of q test showed that there were statistically significant differences in levels of PA and CRP between infection group and control group(P0.05),PA level in infection group decreased,especially in patients with sepsis,bacterial pneumonia,and upper respiratory tract infection;while CRP level in infection group increased,especially in patients with sepsis,bacterial pneumonia,and upper respiratory tract infection.There were statistically significant differences in levels of PA and CRP between patients with severe infection and patients with mild infection in infection group(P0.05),PA level decreased and CRP level increased significantly in patients with severe infection.Conclusion:PA and CRP are good observational indexes to evaluate early diagnosis,illness monitoring,and curative effect of infectious diseases among neonates.