Clinical Study of Zhuyu Xingqi Decoction in the Treatment of Qi Stagnation and Blood Stasis Type Stable Angina Pectoris

OBJECTIVE:To observe the clinical efficacy of Zhuyu xingqi decoction in the treatment of qi stagnation and blood stasis type stable angina pectoris. METHODS:92 patients diagnosed as qi stagnation and blood stasis type stable angina pectoris were randomized into observation group(n=46)and control group(n=46). Two groups were given routine treatment. Control group was additionally given Tongxinluo capsule,and observation group was additionally given Zhuyuxingqi decoction and evidence-based nursing. Treatment course of 2 groups lasted for 3 months. Clinical efficacies of 2 groups were observed,and the effects of treatment on blood lipid,homocysteine and C-reactive protein were also observed. RESULTS:The total effective rates of TCM syndrome and angina pectoris in observation group were higher than in control group(P0.05);total effective rate of ECG was 58.69% in observation group,which was higher than that of the control group(50%). The levels of CRP,Hcy,LDL-C and TG in 2 groups after treatment were significantly lower than before(P0.05),while HDL-C of control group was increased significantly(P0.05). The serum levels of CRP,Hcy,LDL-C,TG and HDL-C level in treatment group were higher than that in control group after treatment(P0.05). CONCLUSIONS:Zhuyu xingqi decoction can significantly improve clinical symptoms and TCM symptoms,reduce the serum level of HCY and CRP and regulate blood lipid in patients with qi stagnation and blood stasis type angina pectoris.