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2004•Pharmaceutical Journal of Chinese People's Liberation ArmyRequires access

Effect of Azone on Permeation of Osthol Through Skin in Vitro

Yuan Zhen

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Abstract

Aim To study the effects of azone on the permeation of osthol through skin in vitro.Methods Valia-Chien diffusion cell was adopted as the apparatus for skin permeation in vitro.Abdomen skin excised from SD rat was pretreated with azone at the different concentrations in vitro.Results Azone at the concentrations of 1%,3%,5% and 7% improved the permeation of osthol through skin.Conclusion Azone can increase the diffusion coefficients of osthol.And the effect of azone is the best when its concentration is 5%.

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What this paper is about

Aim To study the effects of azone on the permeation of osthol through skin in vitro.Methods Valia-Chien diffusion cell was adopted as the apparatus for skin permeation in vitro.Abdomen skin excised from SD rat was pretreated with azone at the different concentrations in vitro.Results Azone at the concentrations of 1%,3%,5% and 7% improved the permeation of osthol through skin.Conclusion Azone can increase the diffusion coefficients of osthol.And the effect of azone is the best when its concentration is 5%.

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Available abstract

Aim To study the effects of azone on the permeation of osthol through skin in vitro.Methods Valia-Chien diffusion cell was adopted as the apparatus for skin permeation in vitro.Abdomen skin excised from SD rat was pretreated with azone at the different concentrations in vitro.Results Azone at the concentrations of 1%,3%,5% and 7% improved the permeation of osthol through skin.Conclusion Azone can increase the diffusion coefficients of osthol.And the effect of azone is the best when its concentration is 5%.

Key concepts: Azone, Permeation, Chemistry, In vitro, Chromatography, Biochemistry, Membrane

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