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The detection of the AmpC and extended-spectrum β-lactamases in Escherichia coli and the analysis of the resistance

Huang Chang-w

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Abstract

Objective To detect the AmpC and the extended-spectrum β-lactamases(ESBLs) in Escherichia coli(E.coli) and to analyze the drug susceptibility. Methods AmpC and ESBLs were detected by improved three dimensional test. Results The detection rates of AmpC,ESBLs and AmpC+ESBLs in E.coli were 3.7%(11/300), (24.7%)(74/300) and 2.3%(7/300) respectively. The resistant rate of the E.coli producting AmpC and ESBLs to 17 kinds of antibiotics was higher than the average. Conclusions Producting AmpC and ESBLs is the main mechanism of resistance in E.coli. Carbopenems could be chosen as clinical experiential medication.

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What this paper is about

Objective To detect the AmpC and the extended-spectrum β-lactamases(ESBLs) in Escherichia coli(E.coli) and to analyze the drug susceptibility. Methods AmpC and ESBLs were detected by improved three dimensional test. Results The detection rates of AmpC,ESBLs and AmpC+ESBLs in E.coli were 3.7%(11/300), (24.7%)(74/300) and 2.3%(7/300) respectively. The resistant rate of the E.coli producting AmpC and ESBLs to 17 kinds of antibiotics was higher than the average. Conclusions Producting AmpC and ESBLs is the main mechanism of resistance in E.coli. Carbopenems could be chosen as clinical experiential medication.

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Available abstract

Objective To detect the AmpC and the extended-spectrum β-lactamases(ESBLs) in Escherichia coli(E.coli) and to analyze the drug susceptibility. Methods AmpC and ESBLs were detected by improved three dimensional test. Results The detection rates of AmpC,ESBLs and AmpC+ESBLs in E.coli were 3.7%(11/300), (24.7%)(74/300) and 2.3%(7/300) respectively. The resistant rate of the E.coli producting AmpC and ESBLs to 17 kinds of antibiotics was higher than the average. Conclusions Producting AmpC and ESBLs is the main mechanism of resistance in E.coli. Carbopenems could be chosen as clinical experiential medication.

Key concepts: Escherichia coli, Microbiology, Drug resistance, Antibiotics, Biology, Antibiotic resistance, Genetics, Gene

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