2011Medical RecapitulateRequires access

Development of Mesenchymal Stem Cells Homing

Shu Ju

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Abstract

Mesenchymal stem cells(MSCs)are non-hematopoietic multipotent stem cells possessing multidifferentiation potential,have deemed as the most promising stem cells for the treatment of a variety of diseases,and have demonstrated significant potential for clinical use,but their low rate of homing to target tissues and organs limit the therapeutic efficacy and the distribution and diferentiation of MSCs after homing directly influence their application when they are used in stem cell therapy.Thus,further research of MSC homing mechanisms and homing factor may lead to the development of therapies with the potential to promote clinical applications of MSCs.

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What this paper is about

Mesenchymal stem cells(MSCs)are non-hematopoietic multipotent stem cells possessing multidifferentiation potential,have deemed as the most promising stem cells for the treatment of a variety of diseases,and have demonstrated significant potential for clinical use,but their low rate of homing to target tissues and organs limit the therapeutic efficacy and the distribution and diferentiation of MSCs after homing directly influence their application when they are used in stem cell therapy.Thus,further research of MSC homing mechanisms and homing factor may lead to the development of therapies with the potential to promote clinical applications of MSCs.

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Available abstract

Mesenchymal stem cells(MSCs)are non-hematopoietic multipotent stem cells possessing multidifferentiation potential,have deemed as the most promising stem cells for the treatment of a variety of diseases,and have demonstrated significant potential for clinical use,but their low rate of homing to target tissues and organs limit the therapeutic efficacy and the distribution and diferentiation of MSCs after homing directly influence their application when they are used in stem cell therapy.Thus,further research of MSC homing mechanisms and homing factor may lead to the development of therapies with the potential to promote clinical applications of MSCs.

Key concepts: Homing (biology), Mesenchymal stem cell, Stem cell, Haematopoiesis, Multipotent Stem Cell, Biology, Cell biology, Immunology

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