Synthesis and herbicidal activity of N-isoindoline-1,3-dione-substituted phenyl-N'-benzoyl ureas

In search of safer and more efficiency herbicidal compounds,flumioxazin was chosen as lead compound,and eleven N-isoindoline-1,3-dione-substituted phenyl-N'-benzoyl ureas were designed and synthesized.Their structures were confirmed by IR,1H NMR,LC/MC and elemental analysis.Preliminary bioassay showed that most of title compounds had better herbicidal activity,for example,5a,5b,5c,5e,5f and 5g exhibited more than 80% inhibition to broad-leaved weeds,such as Abutilon theophrasti,Chenopodium album L.,Amaranthus ascedense L.at 75 g/hm2.