Study of Clinical Significance of Detection of the Parathyroid Hormone in Secondary Hyperparathyroidism Patients with Long-term Hemodialysis

Objective To investigate the applied value of detection of the parathyroid hormone (PTH)on early diagnosis, prophylaxis and treatment in secondary hyperparathyroidism (SHPT) patients with chronic hemodialysis. Methods A total of 84 patients suffered from long-term hemodialysis were divided into calcium treatment group and non-calcium treatment group. 30 patients with normal kidney function served as control group. The levels of serum PTH,calcium,phosphorus,urea nitrogen and creatinine were measured. Results The level of serum PTH and phosphorus of the patients in calcium treatment group was lower than those in non-calcium treatment group (P0. 05). serum calcium level had no difference between in the two groups (P0. 05). The level of serum PTH of hemodialysis patients was positive correlation with urea nil rogen, creatinine and phosphorus, was higher than those in control group significantly. Conclusion The detection of PTH has important role in early diagnosis, prophylaxis and treatment in SHPT patients with chronic hemodialysis and could decrease morbidity rate of hyperparathyroidism.