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2010•National Medical Frontiers of ChinaRequires access

Pathogenesis and Treatment of Metabolic Syndrome

Jingfa Zhang

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Abstract

Metabolic syndrome is a clinical disorder characterized by the accumulation of multi-risk factors. The mechanisms underlying metabolic syndrome are not fully understood. However, insulin resistance, obesity, inflammation, and changes in metabolic factors such as pyruvate 11{beta}-hydroxysteroid dehydrogenase, uncoupling protein, all play roles in the pathogenesis of this syndrome. The therapy of MS is to improve cardiovascular risk factors based on improving IR. This paper makes a summary of the pathogenesis and treatment of metabolic syndrome.

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What this paper is about

Metabolic syndrome is a clinical disorder characterized by the accumulation of multi-risk factors. The mechanisms underlying metabolic syndrome are not fully understood. However, insulin resistance, obesity, inflammation, and changes in metabolic factors such as pyruvate 11{beta}-hydroxysteroid dehydrogenase, uncoupling protein, all play roles in the pathogenesis of this syndrome. The therapy of MS is to improve cardiovascular risk factors based on improving IR. This paper makes a summary of the pathogenesis and treatment of metabolic syndrome.

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Available abstract

Metabolic syndrome is a clinical disorder characterized by the accumulation of multi-risk factors. The mechanisms underlying metabolic syndrome are not fully understood. However, insulin resistance, obesity, inflammation, and changes in metabolic factors such as pyruvate 11{beta}-hydroxysteroid dehydrogenase, uncoupling protein, all play roles in the pathogenesis of this syndrome. The therapy of MS is to improve cardiovascular risk factors based on improving IR. This paper makes a summary of the pathogenesis and treatment of metabolic syndrome.

Key concepts: Pathogenesis, Metabolic syndrome, Medicine, Insulin resistance, Bioinformatics, Metabolic disorder, Inflammation, Obesity

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