2008•Zhongguo redai yixueRequires access

Comparison of detection of serum antinuclear antibody with immunoblotting and indirect immunofluorescence(IIF)

Zheng Hui

Abstract

Objective To investigate the correlation of positive types of ANA Profile 3 EUROLIN and their patterns of the antinuclear antibodies(ANA) by IIF in human serum.Methods Indirect immunofluorescence(IIF)(by HEP-2 cells and primate liver as antigen substrates) and ANA Profile 3 EUROLIN antinuclear antibodies were used to analyze 251 patterns of the ANA and their antibody types respectively.Results There no obvious relationship between positive types of ANA Profile 3 EUROLIN antibodies and their patterns of the ANA by IIF in human serum was observed.Conclusion The patterns of ANA by IIF cannot be used to conclude the types of ANA Profile 3 EUROLIN.

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Key concepts: IIf, Anti-nuclear antibody, Indirect immunofluorescence, Immunofluorescence, Antibody, Biology, Antigen, Molecular biology