Differential Diagnosis of Breast Benign and Malignant Lesions with Three Dimensional Dynamic Contrast and Digital Subtraction MR Imaging

Objective To study the value of three dimensional dynamic contrast and digital subtraction MRI in diagnosing breast cancer. Methods 52 patients with breast diseases were enrolled in this study,including 27 malignant lesions and 36 benign lesions verified by histopathology. The morphologic features and enhancement kinetics of breast lesion on MRI were observed. The morphologic manifestation,early-phase enhancement rate,peak enhancement rate,peak time and time-signal intensity curve were evaluated. Results The benign lesion were mainly characterized by regular mass,well-defined border,internal septation,homogeneous enhancement,and the malignant lesions birregular shape,speculated margin,rim enhancement,inhomogeneous enhancement. The early-phase enhancement rate,peak time and curve type were significantly different between breast benign and malignant lesions(P0.05), but the peak enhancement rate was no significant difference. Conclusion The early-phase enhancement rates,peak time and time-signal intensity curve pattern are very useful in diagnosing breast cancer,but there is an overlapping in some patients.