Granular cell tumor(GCT) of the breast:a clinical pathologic analysis of one case

Objective To study the histopathological characteristic,diagnosis,differential diagnosis and prognosis of Granular cell tumor of the breast.Methods One case of Granular cell tumor of the breast was studied by histopathological observation and immunohistochemical staining.Results No special clinical situations were found in this case and the tumor was charsterized by clear cell boundary,aboundant cytoplasm,full of acidophilic granules and it also in filtrated beyond the edge of the maintumor.Immunohistochemical study demonstrated that tumor cell swerere acted with S-100,VIM,PAS,but negatively with CEA.Those benign ones donot metastasize and such patients have favorable prognosis.Conclusion GCT of the breast,a rarely tumor that can be misdiagnosed by frozensection,clinical and cytological tests.The disease should be enforced to study and avoid being operated excessively and unnecessarily.