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2003•Chinese journal of integrated traditional and Western medicineRequires access

Effect of Haizhu Yigan Capsule on Serum TNF-α and sIL-2R of Patients with Chronic Hepatitis B

Yu Chen

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Abstract

Objective: To observe the effect of Haizhu Yigan capsule on serum TNF-α and sIL-2R of Patients with chronic virus hepatitis B, and analyze the mechanism of its actions. Methods: 60 patients with CHB were assigned randomly to two groups. The treatment group was treated by capsule HZYG orally, and the control group was treated by IFN-α1b. After 3 months' treating, the levels of serum TNF-α and sIL-2R Were determined. Then compared these effects with the control group. Results: After 3 months' treating, both of the 2 groups' level of serum TNF-α and sIL-2R were reduced, compared with the level before treatmentP 0.05. The level between the 2 groups after treatment was no significant different (P 0.05). Conclusion: Both Haizhu Yigan capsule and IFN-α1b can reduce the level of serum TNF-a and sIL-2R, this is also one of the anti-virus mechanism.

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What this paper is about

Objective: To observe the effect of Haizhu Yigan capsule on serum TNF-α and sIL-2R of Patients with chronic virus hepatitis B, and analyze the mechanism of its actions. Methods: 60 patients with CHB were assigned randomly to two groups. The treatment group was treated by capsule HZYG orally, and the control group was treated by IFN-α1b. After 3 months' treating, the levels of serum TNF-α and sIL-2R Were determined. Then compared these effects with the control group. Results: After 3 months' treating, both of the 2 groups' level of serum TNF-α and sIL-2R were reduced, compared with the level before treatmentP 0.05. The level between the 2 groups after treatment was no significant different (P 0.05). Conclusion: Both Haizhu Yigan capsule and IFN-α1b can reduce the level of serum TNF-a and sIL-2R, this is also one of the anti-virus mechanism.

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Available abstract

Objective: To observe the effect of Haizhu Yigan capsule on serum TNF-α and sIL-2R of Patients with chronic virus hepatitis B, and analyze the mechanism of its actions. Methods: 60 patients with CHB were assigned randomly to two groups. The treatment group was treated by capsule HZYG orally, and the control group was treated by IFN-α1b. After 3 months' treating, the levels of serum TNF-α and sIL-2R Were determined. Then compared these effects with the control group. Results: After 3 months' treating, both of the 2 groups' level of serum TNF-α and sIL-2R were reduced, compared with the level before treatmentP 0.05. The level between the 2 groups after treatment was no significant different (P 0.05). Conclusion: Both Haizhu Yigan capsule and IFN-α1b can reduce the level of serum TNF-a and sIL-2R, this is also one of the anti-virus mechanism.

Key concepts: Capsule, Gastroenterology, Medicine, Internal medicine, Tumor necrosis factor alpha, Immunology, Biology, Botany

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Effect of Haizhu Yigan Capsule on Serum TNF-α and sIL-2R of Patients with Chronic Hepatitis B — Research Paper | ScholarLens