2011•Zhongguo shiyan fangjixue zazhiRequires access

Investigations on Chemical Constituents of Methanolic Extract from Penicillium jiangxiense

Liang Guang-yi

Abstract

Objective: To study the chemical constituents of Penicillium jiangxiense.Method: Isolation and purification were carried out on normal phase silica gel,Sephadex LH-20,ODS column chromatography etc.Structures of the compounds isolated were identified by physicochemical properties and spectral analysis.Result: Thirteen compounds were identified as uridine(1),ergosterol(2),1-monoolien(3),2′-deoxyadenosine(4),thymidine(5),D-mannitol(6) palmitic acid(7),20-hydroxydammar-24-en-3-one(8),7,22-dien-3,5,6-triol-ergostane(9),helvolic acid(10),glycerol-β-steariate(11),luteolin(12),nicotinic acid(13).Conclusion: Compounds 4-13 were isolated from P.jiangxiense for the first time.

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Key concepts: Sephadex, Chemistry, Silica gel, Column chromatography, Penicillium, Chromatography, Ergosterol, Chemical constituents