Clinical research of Chaiqin Xiexin decoction addition and subtraction treatment of liver-stomach disharmony chronic superficial gastritis

Objective To investigate the clinical efficacy of Chaiqin xiexin decoction addition and subtraction in the treatment of liver-stomach disharmony chronic superficial gastritis.Methods 120 patients with liver-stomach disharmony chronic superficial gastritis admitted to the municipal hospitals from June 2010 to July 2011 were analyzed retrospectively and divided into the observation group and the control group according to the treatment method,with 60 patients in each group.The observation group was given oral administration of Chaiqin Xiexin decoction addition and subtraction 1 prescription/day;The control group was given oral administration of domperidone tablets 10 mg/day before meals with warm water.With 8 weeks as 1 treatment course,the changes of clinical symptoms and gastroscopic examination of the two groups before and after the treatment were observed and recorded.The clinical efficacy and safety of Chaiqin Xiexin decoction addition and subtraction treatment of liver-stomach disharmony chronic superficial gastritis were evaluated.Results After the treatment,each clinical symptom of both groups significantly improved compared to those before the treatment,with the observation group superior to the control group(t=7.12,7.05 and 7.03,P 0.05 for all);Each indicator of gastroscopic examination significantly improved,with the observation group superior to the control group(t=7.12,7.05 and 7.03,P 0.05 for all).The observation group had a total response rate of 93.3%,which was significantly higher than the 73.3% of the control group(x2=9.572,P 0.05).During the treatment process,no obvious adverse reactions occurred.Conclusion In the treatment of liver-stomach disharmony chronic superficial gastritis,Chaiqin Xiexin decoction addition and subtraction shows significant clinical efficacy and is highly safe,thereby worthy of clinical promotion and application.