Clinical Observation of 3 Kinds Different Ovulation Stimulating Methods on Polycystic Ovary Syndroms (PCOS)

Objective To select the optimum therapy for polycystic ovary syndromes (PCOS) through the clinical observation on the therapeutic effects of three different ovulation-stimulating methods for PCOS. Methods 56 cases of PCOS infertility were randomly divided into three groups, which were treated by: 1.TCD decoction for ovulation (TCDDO) and clomifen citrate (CC) and human chorionic gonadotropin (HCG) (group Ⅰ, n=28); 2. Tamoxifen (TMX) and CC (group Ⅱ, n=20); 3. Human menopausal gonadotropin (HMG) and HCG (group Ⅲ,n=8). The ovulation were monitored by B ultrasound scanning. Results The periodic ovulatory and pregnancy rates of group Ⅰ were 84.52% and 64.3% respectively, those of group Ⅱ were 86.67% and 35.0% and those of Ⅲ were 83.33% and 37.5%. The ovulatory rates of the three groups had no significant differences (P0.05) but the pregnancy rates had significant differences. The pregnancy rate of group Ⅰ was obviously higher than that of group Ⅱ and group Ⅲ (P0.05). No ovary hyper-stimulus syndromes (OHSS) occurred in the three groups. Conclusion The treatment by TCDDO, CC and HCG had an advantage over that by TMX, CC and by HMG, HCG.