The Effectiveness of the Combination between Budesonide an Aminophylline in Patients with COPD and Its Effect on Lung Function

Objective:To explore the effectiveness of the combination between budesonide and aminophylline in patients with chronic obstructive lung disease(COPD) and its effect on lung function.Methods:The definite patients with COPD were randomly allocated into two groups including observation group and control group,each of which had 43 cases.In two groups,all patients received a series of symptomatic treatment such as infectious control,spasmolysis and antiasthmatic treatment,relieving cough and reducing sputum and rectifying disturbance of electrolyte and acid-base balance.In control group,the patients received aminophylline as an additional treatment.Except for that,the patients also inhaled the budesonide atomized liquid in observation group.Results:The total effective rate in observation group was 88.37%,while it was 69.77%in control group.There was significant difference between two groups.The forced vital capaoity(FVC),forced expiratory volume at one second(FEV1) and the ratio of forced expiratory volume to forced vital capacity(FEV1/FVC%) significantly surpassed those before treatment(P0.05 or P0.01).Besides,for the improvement of FVC,FEV1, FEV1/FVC%,there was statistical significance between two groups(P0.05).Conclusions:The inhalation therapy of aminophylline and budesonide can treat COPD,improve lung function,evaluate the clinical effectiveness and deserve to be generalized.