ScholarLens Back to search
2009•Journal of Huaihai MedicineRequires access

Effects of losartan on hypertension and left ventricular hypertrophy

Wang Hong-ta

Open publisher page 0 citations

Abstract

Objective To observe the effects of losartan on hypertension and left ventricular hypertrophy.Methods Thirty patients with essential hypertension(EH) with left ventricular hypertrophy(LVH) were treated with oral losartan 50~100mg,once a day,with a total 16 week course of treatment.The heart structure was checked twice throngh color Doppler ultrasonic cardiography(UCG)to observe the effects of left ventricular remodeling and at the same time to monitor adverse drug reactions.Results EH and LVH showed fine results after the treatment.The blood pressure dropped and the total effective rate was 80%(P0.01).UCG indicated the left ventricular mass index(LVMI) decreased significantly after the treatment(P0.05).Conclusion The long-term use of losartan contributes to blood pressure decrease and reversed left ventricular hypertrophy.It is one of the advisable drugs for left ventricular remodeling.

About this research paper

What this paper is about

Objective To observe the effects of losartan on hypertension and left ventricular hypertrophy.Methods Thirty patients with essential hypertension(EH) with left ventricular hypertrophy(LVH) were treated with oral losartan 50~100mg,once a day,with a total 16 week course of treatment.The heart structure was checked twice throngh color Doppler ultrasonic cardiography(UCG)to observe the effects of left ventricular remodeling and at the same time to monitor adverse drug reactions.Results EH and LVH showed fine results after the treatment.The blood pressure dropped and the total effective rate was 80%(P0.01).UCG indicated the left ventricular mass index(LVMI) decreased significantly after the treatment(P0.05).Conclusion The long-term use of losartan contributes to blood pressure decrease and reversed left ventricular hypertrophy.It is one of the advisable drugs for left ventricular remodeling.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To observe the effects of losartan on hypertension and left ventricular hypertrophy.Methods Thirty patients with essential hypertension(EH) with left ventricular hypertrophy(LVH) were treated with oral losartan 50~100mg,once a day,with a total 16 week course of treatment.The heart structure was checked twice throngh color Doppler ultrasonic cardiography(UCG)to observe the effects of left ventricular remodeling and at the same time to monitor adverse drug reactions.Results EH and LVH showed fine results after the treatment.The blood pressure dropped and the total effective rate was 80%(P0.01).UCG indicated the left ventricular mass index(LVMI) decreased significantly after the treatment(P0.05).Conclusion The long-term use of losartan contributes to blood pressure decrease and reversed left ventricular hypertrophy.It is one of the advisable drugs for left ventricular remodeling.

Key concepts: Losartan, Medicine, Left ventricular hypertrophy, Cardiology, Internal medicine, Blood pressure, Essential hypertension, Muscle hypertrophy

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Effects of losartan on hypertension and left ventricular hypertrophy — Research Paper | ScholarLens