Analysis on Efficiency of Montelukast in the Treatment of Infantile Henoch-Schonlein Purpura

Objective To investigate the clinical effects of montelukast in the treatment of infantile HenochSchonlein purpura(HSP).Methods Sixty children with HSP were randomly divided into treatment group and control group,30 cases in each group.The children in control group were given routine treatment,while those in the treatment group were added montelukast based on the routine treatment.The treatment lasted for 10 days.The clinical effects,time of rash disappearance,abdominal symptomatic remission,joint swelling remission,and adverse effects in two groups were compared.Results The effective rate in the treatment group was significantly higher than in control group.The time of rash disappearance,abdominal symptomatic remission and joint swelling remission in the treatment group were all markedly shorter than in control group.During treatments,there were no apparent adverse reactions were observed in two groups.Conclusion Application of montelukast based on routine treatment in treatment of infantile HSP can quickly alleviate capillary inflammation and clinical symptoms,reduces kidney injury,and has definite clinical effects and higher safety.